RESTORE: Robust intEnSiTy nORmalization mEthod for multiplexed imaging
نویسندگان
چکیده
منابع مشابه
Robust Inter-slice Intensity Normalization Using Histogram Scale-Space Analysis
This paper presents a robust method to correct for intensity differences across a series of aligned stained histological slices. The method is made up of two steps. First, for each slice, a scale-space analysis of the histogram provides a set of alternative interpretations in terms of tissue classes. Each of these interpretations can lead to a different classification of the related slice. A si...
متن کاملARRm: Adaptive Robust Regression method for normalization of methylation data
With the adaptation of microarray hybridization techniques developed for gene expression and genomics studies to methylation data, there has been a revolution in the development of DNA methylation profiling techniques [1]. Illumina recently released the Infinium HumanMethylation450 BeadChip, a single CpG site resolution array using bisulfite-converted DNA. The Infinium 450k methylation array co...
متن کاملMetTailor: dynamic block summary and intensity normalization for robust analysis of mass spectrometry data in metabolomics
MOTIVATION Accurate cross-sample peak alignment and reliable intensity normalization is a critical step for robust quantitative analysis in untargetted metabolomics since tandem mass spectrometry (MS/MS) is rarely used for compound identification. Therefore shortcomings in the data processing steps can easily introduce false positives due to misalignments and erroneous normalization adjustments...
متن کاملA robust neural networks approach for spatial and intensity-dependent normalization of cDNA microarray data
MOTIVATION Microarray experiments are affected by numerous sources of non-biological variation that contribute systematic bias to the resulting data. In a dual-label (two-color) cDNA or long-oligonucleotide microarray, these systematic biases are often manifested as an imbalance of measured fluorescent intensities corresponding to Sample A versus those corresponding to Sample B. Systematic bias...
متن کاملComparison between Different Intensity Normalization Methods in 123I-Ioflupane Imaging for the Automatic Detection of Parkinsonism
Intensity normalization is an important pre-processing step in the study and analysis of DaTSCAN SPECT imaging. As most automatic supervised image segmentation and classification methods base their assumptions regarding the intensity distributions on a standardized intensity range, intensity normalization takes on a very significant role. In this work, a comparison between different novel inten...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Communications Biology
سال: 2020
ISSN: 2399-3642
DOI: 10.1038/s42003-020-0828-1